What is Dolasetron used for?

What is Dolasetron used for?

Dolasetron is used to prevent nausea and vomiting caused by cancer chemotherapy. Dolasetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.

Is Dolasetron discontinued?

Why was Anzemet (dolasetron) discontinued? It’s not clear why the manufacturer stopped making Anzemet (dolasetron). It’s possible that the medication is not as popular or commonly used as other antiemetics, like ondansetron (Zofran) or granisetron.

What is the chemical name of Dolasetron?

Dolasetron (trade name Anzemet) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy….Dolasetron.

What is another name for aprepitant?

Aprepitant, sold under the brand name Emend among others, is a medication used to prevent chemotherapy-induced nausea and vomiting (CINV) and to prevent postoperative nausea and vomiting.

What are the side effect of Dolasetron?

Dolasetron side effects a light-headed feeling, like you might pass out; slow heart rate, weak pulse, slow breathing; swelling in your hands or feet; little or no urinating; or.

What is the mechanism of action of granisetron?

Granisetron is an indazole derivative with antiemetic properties. As a selective serotonin receptor antagonist, granisetron competitively blocks the action of serotonin at 5-hydroxytryptamine3 (5-HT3) receptors, resulting in the suppression of chemotherapy- and radiotherapy-induced nausea and vomiting.

What is the generic name for anzemet?

GENERIC NAME: DOLASETRON – ORAL (doe-LAS-e-tron)

What is the drug classification of Dolasetron and ondansetron?

Dolasetron belongs to a class of medications called 5-HT3 blockers. It works by blocking one of the body’s natural substances (serotonin) that causes vomiting. This form of dolasetron should not be used to prevent nausea or vomiting after surgery because of the risk of serious side effects.

How does an aprepitant work?

Aprepitant is in a class of medications called antiemetics. It works by blocking the action of neurokinin, a natural substance in the brain that causes nausea and vomiting.

What is the half life of aprepitant?

Aprepitant is eliminated by metabolism. In the therapeutic dose range, clearance is 60-72 ml/min and the terminal half-life about 9-13 hours.

Is granisetron a solution?

The solution for injection is a clear, colourless liquid. – acute nausea and vomiting associated with chemotherapy and radiotherapy. – post-operative nausea and vomiting. Granisetron is indicated for the prevention of delayed nausea and vomiting associated with chemotherapy and radiotherapy.