What is promethazine used to treat?
Promethazine is a medication used to manage and treat allergic conditions, nausea and vomiting, motion sickness, and sedation. It also has off-label uses for nausea and vomiting in pregnancy. Promethazine is a phenothiazine derivative with antidopaminergic, antihistamine, and anticholinergic properties.
Can promethazine be given by IV push?
Action Needed to Prevent Serious Tissue Injury with IV Promethazine. Although deep intramuscular injection into a large muscle is the preferred par-enteral route of administration, product labeling states that the drug may be given by slow IV push, which is how it is typically given in most hospitals.
What happened to the patient who received promethazine?
In 2005, a patient received 12.5 mg of promethazine IV into an IV site in the hand. During the injection, the patient complained of extreme burning, but the nurse continued administering the medication. The patient developed an area of necrosis on his hand, eventually requiring skin grafting and physical rehabilitation.
Can promethazine be used for nausea and vomiting during pregnancy?
Nausea and vomiting associated with pregnancy: According to the American College of Obstetrics promethazine is useful in nausea and vomiting during pregnancy when preferred agents do not provide symptomatic relief.
Does promethazine Make you Sleepy?
About promethazine Promethazine is an antihistamine medicine that relieves the symptoms of allergies. It’s known as a drowsy (sedating) antihistamine, so it’s more likely to make you feel sleepy than other antihistamines.
Can promethazine toxicity be predicted from the dose ingested?
Conclusion: The main feature of promethazine toxicity is delirium, the probability of which can be predicted from the dose ingested. The administration of charcoal and the presence of co-ingestants appears to reduce the probability of delirium in a predictable manner.
Is prom promethazine a sedating or sleeping antihistamine?
Promethazine is known as a drowsy (sedating) antihistamine as it makes you sleepy. Non-drowsy antihistamines are less likely to have this effect.