What does sympathomimetic amine mean?
Sympathomimetic drugs (also known as adrenergic drugs and adrenergic amines) are stimulant compounds which mimic the effects of endogenous agonists of the sympathetic nervous system. Examples of sympathomimetic effects include increases in heart rate, force of cardiac contraction, and blood pressure.
What are sympathomimetic side effects?
WHAT ARE SIDE EFFECTS OF SYMPATHOMIMETICS?
- Bad taste in the mouth.
- Blurred vision.
- Chills.
- Constipation.
- Diarrhea.
- Dry mouth.
- Excitement.
- Hair loss.
What drugs are sympathomimetic amines?
Cardiovascular Agents. Sympathomimetic amines (epinephrine, norepinephrine, phenylephrine, dopamine, dobutamine, ephedrine, and isoproterenol) are particularly susceptible to pharmacodynamic drug-drug interactions.
What is the meaning of sympathomimetic drug?
Sympathomimetics are drugs that mimic the stimulation of the sympathetic nervous system. They are classified as directly acting (act directly on α or β receptors), indirectly acting (act by providing more norepinephrine to act on α or β receptors), or mixed acting (act by both mechanisms).
What do Sympatholytics do?
A sympatholytic (or sympathoplegic) drug is a medication that opposes the downstream effects of postganglionic nerve firing in effector organs innervated by the sympathetic nervous system (SNS). They are indicated for various functions; for example, they may be used as antihypertensives.
What is sympathomimetic toxidrome?
The sympathomimetic toxidrome is a combination of physical findings characteristic of overdose of certain classes of drugs, including cocaine and amphetamines.
What actions do sympathomimetic drugs have on the body?
Because these drugs mimic sympathetic adrenergic stimulation, they can produce hypertension, excessive cardiac stimulation and cardiac arrhythmias. For these reasons, most of these drugs are only used for short-term cardiovascular therapy with clinical supervision and monitoring.
Which one is a sympathomimetic drug?
Direct sympathomimetic drugs
| Overview of direct sympathomimetics | |
|---|---|
| Drugs | Action |
| Epinephrine | β > α (at high doses the α effect is predominant) Stronger β2-receptor effect than norepinephrine |
| Fenoldopam | D1 Vasodilates coronary and peripheral vessels Promotes natriuresis |
| Isoproterenol | β1 = β2 Marginal α effect |
Is epinephrine a sympathomimetic?
Epinephrine is a sympathomimetic catecholamine that exerts its pharmacologic effects on both alpha and beta-adrenergic receptors using a G protein-linked second messenger system.
What is sympatholytic and sympathomimetic?
Sympathomimetics and Sympatholytics: Introduction Drugs that bind to these receptors and modulate or mimic the function of the sympathetic nervous system may be divided into those which augment the system (sympathomimetics) and those which antagonize the system (sympatholytics).
What causes sympathomimetic?
The etiology of acute sympathomimetic toxicity is related to its effect on the inhibition of norepinephrine and dopamine reuptake at the preganglionic synapse. This can be due to any of the number of sympathomimetics, with the prototypical drug being cocaine.