How is sestamibi administered?
Technetium (99mTc) sestamibi is a lipophilic cation which, when injected intravenously into a patient, distributes in the myocardium proportionally to the myocardial blood flow.
What type of surgeon removes parathyroid tumors?
To treat hyperparathyroidism, a surgical oncologist removes the parathyroid gland.
What is a sestamibi injection?
Sestamibi is a small protein which is labeled with the radio-pharmaceutical technetium99. This very mild and safe radioactive agent is injected into the veins of a patient with hyperparathyroidism (parathyroid disease) and is absorbed by the overactive parathyroid gland.
What specialty is parathyroidectomy?
Duke endocrine surgeons perform parathyroid surgery to remove abnormal parathyroid glands or tissue. The glands are located behind the thyroid gland in the neck. Parathyroidectomy may be recommended as treatment when hyperparathyroidism or parathyroid cancer is present.
How does sestamibi scan work?
Therefore, a sestamibi scan will show the one bad parathyroid tumor and it will NOT show your normal parathyroid glands. When an x-ray machine is placed over the patient’s neck an accurate picture will show the overactive gland and where it is located in your neck.
How accurate are sestamibi scans?
Research indicates that a sestamibi scan helps a doctor identify an abnormal parathyroid gland in approximately 85% of all cases when PTH levels are over 150 ng/ml. The accuracy is much lower at lower PTH levels.
How much radiation is in a sestamibi scan?
The mean radiation dose of dynamic parathyroid CT was 5.56 mSv, while sestamibi scintigraphy delivered a mean radiation dose of 3.33 mSv (P < . 05).
What is a sestamibi scan?
Sestamibi scanning is the preferred way to localize diseased parathyroid glands prior to an operation. HOWEVER, sestamibi scans are wrong at least 50% of the time, even at the best places in the world. Be careful folks! This scan was invented in the early 1990’s…
How long does it take for sestamibi to work?
When combined with the probe in the operating room (the MIRP mini parathyroid operation), and examination of the other glands, the cure rate can be over 99%. It takes approximately two hours for most places to perform a Sestamibi scan. Pictures of the neck and chest are usually taken immediately after the injection and again 1.5 to 2.0 hours later.
How is sestamibi reconstituted and administered?
When Sestamibi is reconstituted with Tc99m pertechnetate, a complex of Tc99m Sestamibi is formed and is the active ingredient of the reconstituted product. When administered intravenously, Tc99m Sestamibi shows rapid myocardial uptake and its distribution follows a linear relationship with coronary blood flow.
What is technetium Tc 99m sestamibi injection?
Drug Label Information. Myocardial Imaging: Technetium Tc 99m Sestamibi Injection is a myocardial perfusion agent that is indicated for detecting coronary artery disease by localizing myocardial ischemia