What is ovarian stromal Luteoma?
Stromal luteomas constitute 20 to 25% and are always benign. They are the tumours which are compromised of small steroid cells in the ovarian stroma, whereas Leydig cell tumours are usually localised in the hilus of the ovary (Sternberg and Roth 1973. 1973. Ovarian stromal tumors containing Leydig cells.
What is a Luteoma?
Luteoma of pregnancy is a rare, benign condition characterized by a tumor-like mass of the ovary that emerges during pregnancy and regresses spontaneously after delivery. It is usually asymptomatic and the diagnosis is generally incidental.
What is a stromal tumor of the ovary?
Ovarian stromal tumors develop in the ovaries’ structural connective tissue cells that produce the female hormones estrogen and progesterone. Stromal cells are among the three most common cell types to be affected by ovarian cancer; however, stromal tumors represent only about 1% of all ovarian cancers.
What is sclerosing stromal tumor?
Sclerosing stromal tumors are an uncommon type of benign ovarian sex cord-stromal tumor. Histologically, they are characterized by a cellular pseudolobular pattern, composed of fibroblasts and round cells separated by densely collagenous or markedly edematous hypocellular tissue and prominent vascularity.
What is stromal Hyperthecosis?
The term hyperthecosis refers to the presence of nests of luteinized theca cells in the ovarian stroma due to differentiation of the ovarian interstitial cells into steroidogenically active luteinized stromal cells (picture 1). The result is greater production of androgens.
What causes a Luteoma?
Abstract. Pregnancy luteomas are rare, benign, neoplasms of the ovary thought to be caused by the hormonal effects of pregnancy. They are usually asymptomatic and found incidentally during imaging or surgery.
What causes follicular cyst?
What causes follicular cysts? Follicular cysts develop as the result of normal menstrual cycles. If you’re a fertile woman of reproductive age, your ovaries develop cyst-like follicles every month. These follicles produce the important hormones, estrogen and progesterone.
Can ovarian stromal tumors be benign?
There are different types of ovarian sex cord stromal tumours (SCSTs). These can be non cancerous (benign) or cancerous (malignant). Granulosa cell tumours are the most common type.
How is an ovarian stromal tumor treated?
These cancers are treated with surgery to remove the ovary with the tumor. Surgery is also used to stage and debulk the cancer, as needed. This may be followed by chemo or hormone therapy. Often, the chemo used is the same type used to treat germ cell tumors (PEB: cisplatin, etoposide, and bleomycin).
What is a fibroma of the ovary?
An ovarian fibroma is a growth or tumor that appears near a woman’s ovaries and is typically benign (not cancerous). Most instances of ovarian fibroma develop gradually and have no symptoms. In many cases, a benign ovarian fibroma does not cause the patient any trouble and may not require fibroid treatment.
What is stromal luteoma?
tion in the ovarian stroma and probable origin from luteinized stromal cells, which are pres- ent in aggregates elsewhere in the ovaries. Six personally observed cases and 5 tumors of simi- lar nature uncovered in a review of the litera- ture form the basis of the report. The term “stromal luteoma” is proposed for this dis-
What are luteinized stromal cells?
from luteinized stromal cells, which are pres- ent in aggregates elsewhere in the ovaries. Six personally observed cases and 5 tumors of simi- lar nature uncovered in a review of the litera- ture form the basis of the report.
What do luteinized stromal cells in ovarian cancer look like?
In all of the cases, the ovarian stroma out- side the tumor and in the opposite ovary con- tained nests of luteinized stromal cells that bore a striking resemblance to the tumor cells except for a somewhat larger size (Fig. 13); the cells of the luteinized focuses in 2 cases were notable for an abundant content of lipochrome
What is the pathophysiology of pregnancy luteoma?
“pregnancy luteoma” for a variety of lipoid- cell tumor that appears during pregnancy, and he speculated that such a neoplasm might originate from stromal cells that undergo luteinization as a result of stimulation by chorionic gonadotropin. Morris and Scullys suggested that certain lipoid-cell tumors oc-